Henk-Jan Guchelaar Selected Research

Parkinson Disease (Parkinson's Disease)

1/2012	Dopamine agonists and ischemic complications in Parkinson's disease: a nested case-control study.
2/2010	Novel insights in pharmacogenetics of drug response in Parkinson's disease.
12/2009	Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinson's disease.
10/2008	Discontinuation of ropinirole and pramipexole in patients with Parkinson's disease: clinical practice versus clinical trials.
2/2007	Pharmacogenetics of antiparkinsonian drug treatment: a systematic review.
2/2007	Influence of initial use of serotonergic antidepressants on antiparkinsonian drug use in levodopa-using patients.

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Henk-Jan Guchelaar Research Topics

Disease

44	Neoplasms (Cancer) 10/2022 - 06/2004
21	Rheumatoid Arthritis 01/2020 - 04/2006
20	Colorectal Neoplasms (Colorectal Cancer) 10/2022 - 01/2009
16	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2009
14	Renal Cell Carcinoma (Grawitz Tumor) 06/2022 - 02/2011
9	Drug-Related Side Effects and Adverse Reactions 01/2020 - 06/2003
6	Parkinson Disease (Parkinson's Disease) 01/2012 - 02/2007
5	Osteosarcoma (Osteogenic Sarcoma) 01/2020 - 01/2015
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/2019 - 10/2015
5	Neutropenia 10/2011 - 01/2007
4	Dihydropyrimidine Dehydrogenase Deficiency 01/2022 - 07/2015
4	Body Weight (Weight, Body) 01/2021 - 12/2003
4	Leukopenia 02/2017 - 09/2009
4	Vomiting 01/2012 - 02/2011
3	Adrenocortical Carcinoma 01/2021 - 04/2011
3	Hand-Foot Syndrome 01/2020 - 09/2009
3	Neoplasm Metastasis (Metastasis) 01/2020 - 07/2015
3	Nausea 01/2012 - 02/2011
2	Brain Neoplasms (Brain Tumor) 05/2022 - 05/2016
2	Inflammation (Inflammations) 01/2022 - 09/2009
2	Virus Diseases (Viral Diseases) 01/2022 - 04/2011
2	COVID-19 01/2022 - 11/2021
2	Mucositis 01/2022 - 01/2020
2	Peripheral Nervous System Diseases (PNS Diseases) 01/2022 - 11/2016
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2022 - 12/2017
2	Hypersensitivity (Allergy) 12/2021 - 01/2020
2	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 10/2019 - 12/2008
2	Exanthema (Rash) 01/2018 - 01/2012
2	Necrosis 02/2017 - 02/2007
2	Ototoxicity 05/2016 - 01/2014
2	Hearing Loss (Hearing Impairment) 05/2016 - 01/2014
2	Carcinogenesis 01/2016 - 07/2010
2	Thrombosis (Thrombus) 09/2013 - 12/2010
2	Myocardial Infarction 09/2013 - 01/2013
2	Melanoma (Melanoma, Malignant) 07/2013 - 11/2009

Drug/Important Bio-Agent (IBA)

37	Pharmaceutical PreparationsIBA 01/2022 - 06/2003
14	Capecitabine (Xeloda)FDA Link 01/2020 - 06/2008
14	Methotrexate (Mexate)FDA LinkGeneric 01/2020 - 04/2006
11	Tamoxifen FDA LinkGeneric 01/2021 - 01/2009
10	Sunitinib (Sutent)FDA Link 06/2022 - 09/2009
9	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2021 - 01/2009
8	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020 - 03/2009
7	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 04/2004
7	Cetuximab (Erbitux)FDA Link 12/2020 - 07/2010
7	Bevacizumab (Avastin)FDA Link 01/2018 - 01/2009
7	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 01/2009
6	Irinotecan (Camptosar)FDA LinkGeneric 01/2022 - 11/2005
6	EnzymesIBA 01/2021 - 04/2006
6	4-hydroxy-N-desmethyltamoxifenIBA 01/2020 - 11/2013
5	2-mercaptopurineIBA 07/2019 - 10/2015
5	Tyrosine Kinase InhibitorsIBA 01/2018 - 12/2009
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2017
4	Imatinib Mesylate (Gleevec)FDA Link 10/2019 - 12/2007
4	Biological ProductsIBA 01/2019 - 05/2010
4	Cisplatin (Platino)FDA LinkGeneric 05/2016 - 04/2011
3	Panitumumab (Vectibix)FDA Link 10/2022 - 09/2015
3	treosulfanIBA 01/2022 - 12/2017
3	Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA 01/2021 - 07/2015
3	Mitotane (Lysodren)FDA Link 01/2021 - 04/2011
3	thiopurine methyltransferase (thiopurine S-methyltransferase)IBA 07/2019 - 01/2014
3	ErbB Receptors (EGF Receptor)IBA 01/2018 - 01/2011
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 12/2013
3	Adalimumab (Humira)FDA Link 07/2017 - 02/2007
3	Genetic Markers (Genetic Marker)IBA 06/2015 - 10/2006
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2014 - 06/2004
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 08/2004 - 01/2001
2	Antidepressive Agents (Antidepressants)IBA 12/2022 - 02/2007
2	PlatinumIBA 05/2022 - 12/2010
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 10/2011
2	UracilIBA 01/2022 - 07/2015
2	Monoclonal AntibodiesIBA 01/2022 - 09/2011
2	Allopurinol (Remid)FDA LinkGeneric 12/2021 - 01/2020
2	Carbamazepine (Tegretol)FDA LinkGeneric 12/2021 - 01/2020
2	abacavir (Ziagen)FDA Link 12/2021 - 01/2020
2	HLA-B Antigens (HLA-B)IBA 12/2021 - 01/2020
2	Busulfan (Busulfex)FDA Link 01/2021 - 08/2008
2	Cytochrome P-450 CYP2C19IBA 01/2021 - 09/2013
2	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 10/2019 - 12/2003
2	Tumor Necrosis Factor InhibitorsIBA 01/2019 - 07/2017
2	TabletsIBA 03/2018 - 02/2004
2	Cytochrome P-450 CYP2D6 InhibitorsIBA 01/2018 - 05/2010
2	Estrogen ReceptorsIBA 01/2018 - 01/2014
2	AntibodiesIBA 01/2018 - 09/2011
2	ProdrugsIBA 10/2017 - 12/2009
2	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 10/2017 - 02/2017
2	Azathioprine (Imuran)FDA LinkGeneric 10/2017 - 02/2017
2	Cytochrome P-450 CYP3AIBA 10/2015 - 06/2010
2	exemestane (Aromasin)FDA Link 04/2014 - 01/2014
2	Hormones (Hormone)IBA 04/2014 - 01/2012
2	Liposomes (Liposome)IBA 12/2013 - 02/2012
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 07/2013 - 11/2009
2	Etanercept (Enbrel)FDA Link 03/2013 - 02/2007
2	Antirheumatic Agents (DMARD)IBA 07/2012 - 10/2006
2	Taxoids (Taxanes)IBA 01/2012 - 04/2004
2	Dopamine Agonists (Dopamine Agonist)IBA 01/2012 - 12/2009
2	AntiemeticsIBA 01/2012 - 10/2011

Therapy/Procedure

25	Therapeutics 01/2022 - 02/2002
14	Drug Therapy (Chemotherapy) 01/2020 - 06/2004
4	Drug Tapering 10/2019 - 10/2015
2	Stem Cell Transplantation 04/2011 - 11/2010